A Single-Arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Aesthetic or Reconstructive Surgeries
NCT06887972 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2025-12-15
Summary
The purpose of this study to evaluate the effectiveness, safety, and tolerability of SUZ as part of multimodal therapy (MMT) in treating acute postoperative pain.
Conditions
- Acute Pain
Interventions
- DRUG
-
Suzetrigine
Tablets for oral administration.
Sponsors & Collaborators
-
Vertex Pharmaceuticals Incorporated
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-03-21
- Primary Completion
- 2025-10-24
- Completion
- 2025-11-07
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
NCT07145346 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE4
-
Analgesic Treatment Mediated by Arcoxia (0663-093)
NCT00380523 ·Status: COMPLETED ·Phase: PHASE4
-
A Dose-ranging Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy
NCT03764072 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating Efficacy and Safety of VX-993 for Acute Pain After a Bunionectomy
NCT06619847 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 3 Efficacy and Safety Study of VVZ-149 Injections for Postoperative Pain Following Bunionectomy
NCT04430088 ·Status: UNKNOWN ·Phase: PHASE3
-
An Open-Label Functionality, Safety and Efficacy Study in Patients Undergoing Elective Unilateral Knee Replacement
NCT00859313 ·Status: COMPLETED ·Phase: PHASE2
-
Prospective Analgesic Compound Efficacy (PACE) Study
NCT02403687 ·Status: COMPLETED
-
Safety and Efficacy of Sufentanil NanoTab for Management of Acute Pain Following Bunionectomy
NCT01710345 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
NCT04977336 ·Status: COMPLETED ·Phase: PHASE2
-
Fentanyl Transdermal Matrix Patch ZR-02-01 to Treat Chronic, Moderate to Severe Osteoarthritis (OA) Pain
NCT00108771 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of Patient Controlled Analgesia Using the Sublingual Sufentanil Tablet System (SSTS) in a Fast Track Rehabilitation Program After Total Knee Arthroplasty
NCT04432428 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy
NCT03206749 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain With an Open-label Extension
NCT01484652 ·Status: COMPLETED ·Phase: PHASE3
-
A Multicenter, Randomized, Placebo-Controlled Phase 2 Study to Evaluate the Clinical Efficacy, Safety, and Tolerability of ARX-F01 Sublingual Sufentanil in Patients Undergoing Elective Unilateral Total Knee Replacement
NCT00612534 ·Status: COMPLETED ·Phase: PHASE2
-
Peri-articular Injection Utilizing a Pain Cocktail With and Without Exparel
NCT02571283 ·Status: WITHDRAWN ·Phase: PHASE4
-
Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty
NCT03859024 ·Status: COMPLETED ·Phase: PHASE4
-
Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery
NCT04633837 ·Status: TERMINATED ·Phase: NA
-
Celecoxib for ENT Pain Management
NCT06505187 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety Trial to Evaluate the Sufentanil NanoTab® PCA System/15 mcg (Zalviso™) for Post-Operative Pain in Patients After Knee or Hip Replacement Surgery
NCT01660763 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the OrthoCor Active System for Pain Relief
NCT05244187 ·Status: COMPLETED ·Phase: NA
-
Sufentanil Sublingual Tablet System for Postoperative Pain Management After Total Knee Arthroplasty
NCT04448457 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Buprenorphine Transdermal Patch in Non-cancer Pain of Moderate Intensity
NCT02519387 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of TLC590 for Postsurgical Pain Following Bunionectomy
NCT07222748 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Postoperative Analgesia in Bunionectomy
NCT00890682 ·Status: COMPLETED ·Phase: PHASE3
-
Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arthroplasty
NCT02713490 ·Status: COMPLETED ·Phase: PHASE4