MedTrace Logo

Telomeres Length in Israeli Fibrotic ILD Patients

NCT06885515 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-02-25

No results posted yet for this study

Summary

Individuals with fibrotic interstitial lung diseases (FILD) will be recruited after providing informed consent. in addition to routine data as usually collected in the clinic, blood samples will be taken for measurement of telomeres length in peripheral blood leukocytes using both the Telomere Restriction Fragment (TRF) Analysis method and Nanopore sequencing. Participants with FILD will be followed-up for 2-year after recruitment, including clinical and pulmonary function tests at-least every 6 months, or more frequently, according to the treating physician discretion.

Conditions

Interventions

DIAGNOSTIC_TEST

leukocyte telomere length (LTL) will be measured using the Telomere Restriction Fragment (TRF) Analysis method

Peripheral blood leukocytes telomere length will be measured both by TRF analysis and by Nanopore sequencing. Both analyses will be conducted at the laboratory of Prof. Yehuda Tzfati at the Hebrew University, which is highly experienced in the field of telomere biology and in telomere length analysis. Blood samples will be taken once from each participant. No genetic sequencing will be performed as part of this study.

Sponsors & Collaborators

  • Tel Aviv Medical Center

    collaborator OTHER

  • Israel Society of Pulmonology

    collaborator UNKNOWN

  • Barzilai Medical Center

    lead OTHER

Principal Investigators

  • Ori Wand, Dr. · Barzilai University Medical Canter

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-02-28
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Israel

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06885515 on ClinicalTrials.gov