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Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars

NCT06880952 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 145

Last updated 2025-03-18

No results posted yet for this study

Summary

This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal

In this prospective, randomized controlled trial,130 patients who underwent mandibular third molar surgical removal were divided into two groups: one group used chlorhexidine for postoperative rinsing and the other did not rinse. Pain levels, measured using the Numeric Rating Scale (NRS), were recorded daily for the first seven days post-surgery. Paired-samples t-tests were utilized for data analysis.

Conditions

  • Third Molars Extraction

Interventions

OTHER

Chlorhexidine Digluconate Mouthwash without Alcohol

In the rinsing group, the patients received a bottle of 0,2% chlorhexidine

Sponsors & Collaborators

  • Isala

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2022-03-24
Completion
2022-08-19

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06880952 on ClinicalTrials.gov