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Effect of an Experimental Gel Containing Copaiba Oil-resin in the Control of Dentin Hypersensitivity

NCT06872749 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2025-05-20

No results posted yet for this study

Summary

This randomized, single-blind, placebo-controlled clinical trial aims to clinically evaluate the effect of an experimental gel containing copaiba oleo-resin in the control of dentin hypersensitivity (DH) in non-carious cervical lesions (NCCL). Seventy-five hypersensitive teeth will be selected into three groups (N=25) and approved in three treatment sessions. The groups will be: GROUP P= water-soluble placebo gel without active ingredient; GROUP KF2: Potassium nitrate 5% + Sodium fluoride 2%; GROUP GC: Gel containing copaiba oleo-resin. A visual analogue scale (VAS) will be used to compare the DH after tactile stimulation with an exploratory probe and evaporative stimulation with air jets. The DH assessments will be performed at four times: baseline, after 1 week, 15 days and 30 days after the beginning of treatment.

Conditions

  • Pain
  • Dentin Sensitivity
  • Dentin Desensitizing Agents

Interventions

OTHER

Placebo gel

will receive the application of a placebo gel (without active ingredient), under the same conditions described for the experimental gel.

OTHER

KF2 (Potassium nitrate gel)

will receive application of potassium nitrate gel on hypersensitive dental surfaces, in an active way, for 10 minutes.

OTHER

experimental Copaiba gel

will receive the application of the experimental desensitizing gel on the vestibular surfaces of the hypersensitive teeth in an active manner, for 10 minutes.

Sponsors & Collaborators

  • Universidade Federal do Para

    lead OTHER

Principal Investigators

  • Cecy M Silva, Doctor · universidade federal do pará

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-20
Primary Completion
2025-03-10
Completion
2025-03-10

Countries

  • Brazil

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06872749 on ClinicalTrials.gov