Heterogeneity of Oral Squamous Cell Carcinoma Analysis by Single Cell RNA Sequencing

NCT06861036 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-03-06

No results posted yet for this study

Summary

The goal of this project is to characterise the heterogeneity of all cell populations (tumour cells, stromal and immune microenvironment) present in the tumor and their normal (and leucoplasic) counterparts by scRNAseq in OSCC patients.

Conditions

  • Oral Squamous Cell Carcinomas

Interventions

PROCEDURE

Biospecimen

* 1 or 2 tumoral specimen (depending on the size of the tumor) * 1 specimen of the healthy oral mucosa * 1 leucoplakia specimen if applicable. The biospecimens will be collected at the time of the surgery organised for the standard routine medical care.

PROCEDURE

Blood sampling

Blood sampling (6 mL), taken from a routine biological exam.

Sponsors & Collaborators

  • Centre Leon Berard

    lead OTHER

Principal Investigators

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-05-15
Primary Completion
2028-05-15
Completion
2028-05-15

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06861036 on ClinicalTrials.gov