Heterogeneity of Oral Squamous Cell Carcinoma Analysis by Single Cell RNA Sequencing
NCT06861036 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2025-03-06
Summary
The goal of this project is to characterise the heterogeneity of all cell populations (tumour cells, stromal and immune microenvironment) present in the tumor and their normal (and leucoplasic) counterparts by scRNAseq in OSCC patients.
Conditions
- Oral Squamous Cell Carcinomas
Interventions
- PROCEDURE
-
Biospecimen
* 1 or 2 tumoral specimen (depending on the size of the tumor) * 1 specimen of the healthy oral mucosa * 1 leucoplakia specimen if applicable. The biospecimens will be collected at the time of the surgery organised for the standard routine medical care.
- PROCEDURE
-
Blood sampling
Blood sampling (6 mL), taken from a routine biological exam.
Sponsors & Collaborators
-
Centre Leon Berard
lead OTHER
Principal Investigators
-
Philippe Zrounba, M.D. · [email protected]
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-05-15
- Primary Completion
- 2028-05-15
- Completion
- 2028-05-15
Countries
- France
Study Locations
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