Myocardialbridge Bypass Graft Surgery Efficacy Verification

Summary

Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.

Conditions

• Myocardial Bridge of Coronary Artery
• Myocardial Bridge
• Myocardial Bridging
• Myocardial Infarction
• Myocardial Ischemia
• Pectoris, Stable Angina
• Sudden Cardiac Death
• Bypass Graft Stenosis
• Bypass Graft Occlusion
• Bypass Graft Thrombosis

Interventions

PROCEDURE

MBBG

The patients with deep(depth\>2mm) and long-segement(length\>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.

PROCEDURE

MB CABG

The patients with deep(depth\>2mm) and long-segement(length\>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The moderate-to-severe atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography.

PROCEDURE

MB unroof

The patients with superficial type(depth\<2mm) and short-segement(length\<25mm) of myocardial bridge will be allocated to receive myocardialbridge "unroof" surgery，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The MB was superficial and short confirmed by coronory artery CT angiography.

Sponsors & Collaborators

• Xi'an International Medical Center Hospital

  lead OTHER

Principal Investigators

• Zhen Wang, Doctorate · Xi'an International Medical Center Hospital Affiliated To Northwest University

• Jinzhou Zhang, Doctorate · Xi'an International Medical Center Hospital Affiliated To Northwest University

• Jinzhou Zhang, Doctorate · Xi'an International Medical Center Hospital Affiliated To Northwest University

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2020-01-01

Primary Completion

2030-12-31

Completion

2040-12-31

Countries

• China

Study Locations