A Chatbot To Support Substance Use Recovery
NCT06845878 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 55
Last updated 2026-04-20
Summary
The goal of this clinical trial is to learn if/how an AI chatbot can support patients who in recovery for substance use, specifically those who are receiving medication for opioid use disorder.
Can the chatbot help lower drug use? Can the chatbot help improve clinical appointment adherence? Can the chatbot help patients build self-efficacy in leading their own recovery journey? Will the chatbot help reduce workload burden for primary care teams? Can the chatbot serve as a safe, useful and engaging tool to support patients?
Researchers will investigate the effects of using a chatbot to support follow-up care for patients in opioid use recovery.
Participants will:
* Receive access to a chatbot for 12 weeks that they can use to prepare for upcoming clinical appointments, find community resources, learn about urge-surfing and wellness techniques, and query for assistance with other recovery-related information and tasks
* Complete surveys and provide user feedback
Conditions
- Opiate-Related Disorders
- Opiate Substitution Treatment
Interventions
- OTHER
-
chatbot
Participants will: * Participate in a baseline session to complete an initial survey and get trained on using the chatbot * Use the chatbot for 12 weeks and submit a brief weekly survey to provide feedback * Complete a final survey to provide substance use and health information as well as give feedback on the experience using the chatbot * Allow access to a limited set of demographic, substance use and health information in electronic health record for study analyses and context.
Sponsors & Collaborators
-
National Institute on Drug Abuse (NIDA)
collaborator NIH -
University of California, Los Angeles
collaborator OTHER -
Massachusetts General Hospital
collaborator OTHER -
Dimagi Inc.
lead INDUSTRY
Principal Investigators
-
Y. Xian Ho, PhD · Dimagi Inc.
-
Jonathan Jackson, MEng · Dimagi Inc.
Study Design
- Allocation
- NA
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-03-07
- Primary Completion
- 2026-06-01
- Completion
- 2026-08-31
Countries
- United States
Study Locations
More Related Trials
-
Step Away: Comparing a Chatbot-delivered Alcohol Intervention With a Smartphone App
NCT04447794 ·Status: COMPLETED ·Phase: NA
-
Substance Abuse Treatment for High Risk Chronic Pain Patients on Opioid Therapy
NCT00988962 ·Status: COMPLETED ·Phase: NA
-
Reducing Drug Use in Justice-Involved Emerging Adults
NCT05834881 ·Status: COMPLETED ·Phase: NA
-
ClientBot: a Conversational Agent That Supports Skills Practice and Feedback for Motivational Interviewing
NCT05479890 ·Status: COMPLETED ·Phase: NA
-
Research and Engagement on Substance Use: Harnessing Awareness and Personalized Education (RESHAPE) to Improve Well-being and Self-efficacy
NCT06952491 ·Status: ENROLLING_BY_INVITATION
-
Dynamic Assessment and Referral System - Evaluation
NCT01153373 ·Status: COMPLETED ·Phase: PHASE2
-
Computerized Screening, Brief Intervention, and Referral to Treatment in Primary Care
NCT01003834 ·Status: COMPLETED ·Phase: NA
-
How Avatar Can Enhance Autobiographical Memory of Patients With Substance Use Disorder
NCT06806943 ·Status: COMPLETED ·Phase: NA
-
Digitally Assisted Recovery Coach
NCT05393544 ·Status: COMPLETED ·Phase: NA
-
Mobile Continuing Care Approach for Youth
NCT01632735 ·Status: COMPLETED ·Phase: NA
-
Early Re-Intervention Experiment 2
NCT01153594 ·Status: COMPLETED ·Phase: PHASE3
-
Chatbot-delivered Screening and Brief Intervention for Alcohol Reduction in Working-age Adults
NCT06602882 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Monitoring and Feedback in Substance Abuse Treatment
NCT01465490 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Initiating Substance Use Disorder Treatment for Hospitalized Alcohol Use Disorder Patients
NCT04223011 ·Status: WITHDRAWN ·Phase: NA
-
An Evaluation of the Pink Cloud Application in Post- Treatment Substance Use Disorder Support
NCT07042451 ·Status: RECRUITING ·Phase: NA
-
Substance Use Treatment and Recovery Team
NCT05086796 ·Status: COMPLETED ·Phase: NA
-
Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches
NCT05847621 ·Status: COMPLETED ·Phase: NA
-
Implementation of TBI-RECOVER in Substance Use Treatment
NCT07215221 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Using Technology to Reduce Youth Substance Use
NCT04446910 ·Status: COMPLETED ·Phase: NA
-
Machine Learning Technology in Predicting Relapse and Implementing Peer Recovery Intervention Before Drug Use Occurs
NCT05976672 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
The Total Health Study
NCT01415206 ·Status: COMPLETED ·Phase: NA
-
Using Values to Enhance Inmates' Response to Substance Use and HIV Risk Feedback
NCT03501732 ·Status: UNKNOWN ·Phase: NA
-
Web-based Cognitive-behavior Therapy (CBT) for Opioid-treated, Chronic Pain Patients With Aberrant Behavior
NCT01498510 ·Status: COMPLETED ·Phase: NA
-
An Arts Intervention for Drug-Using Homeless Youth
NCT00862238 ·Status: COMPLETED ·Phase: PHASE2
-
Socializing a Science-Based Digital Therapeutic for Substance Use Disorders
NCT05648786 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA