A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors.
NCT06836492 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2025-02-20
Summary
The purpose is to explore the efficacy and safety of the SYSUCC-RMS regimen for pediatric RMS patients and to explore the impact of concurrent radiotherapy and chemotherapy on the survival rate of low-risk, medium risk, high-risk, and extremely high-risk patients in children.
Conditions
- Rhabdomyosarcoma
- Pediatric Cancer
Interventions
- COMBINATION_PRODUCT
-
VAC,VAC/VII,CAV/IE
Low risk: VAC Intermediate risk: VAC/VII High risk: CAV/IE Very high risk: CAV/VIP
Sponsors & Collaborators
-
Yizhuo Zhang
lead OTHER
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 0 Years
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2017-01-30
- Primary Completion
- 2029-09-30
- Completion
- 2029-12-31
Countries
- China
Study Locations
More Related Trials
-
Neoadjuvant Camrelizumab in Combination With Cisplatin and Nab-paclitaxel in Resectable HNSCC
NCT04826679 ·Status: RECRUITING ·Phase: PHASE2
-
Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy
NCT07328841 ·Status: RECRUITING ·Phase: PHASE3
-
Combined Modality Treatment for Resectable Non-Small Cell Superior Sulcus Tumors
NCT00984997 ·Status: COMPLETED ·Phase: PHASE2
-
Induction Chemotherapy Followed By Chrono-chemotherapy Concurrent With IMRT Of Locally Advanced NPC Clinical Study
NCT02187315 ·Status: UNKNOWN ·Phase: PHASE2
-
40.2Gy Versus 49.2Gy Radiotherapy in Low-Risk Target Volume for Chemosensitive Stage II Nasopharyngeal Carcinoma
NCT07328854 ·Status: RECRUITING ·Phase: PHASE3
-
A Clinical Research of NK Cell Infusion Combined With Chemotherapy in the Treatment of Non-small Cell Lung Cancer
NCT02734524 ·Status: UNKNOWN ·Phase: PHASE2
-
Reduced-dose RT With/Without CCT Versus Standard CCRT for High-risk LANPC Who Achieved CR Post Induction Chemotherapy
NCT06092957 ·Status: RECRUITING ·Phase: PHASE3
-
The Neoadjuvant Treatment of Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma.
NCT05170542 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Therapy of GP Chemotherapy Combined With Tislelizumab in Locoregionally Advanced NPC
NCT04833257 ·Status: COMPLETED ·Phase: PHASE2
-
A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 01(NSCLC)]
NCT06783647 ·Status: RECRUITING ·Phase: PHASE2
-
Two-cycle and Three-cycle Induction Therapy With Modified TPF Regimen Combined and Camrelizumab for LANPC
NCT06811844 ·Status: RECRUITING ·Phase: PHASE2
-
Combination of Concurrent Chemoradiotherapy With Surufatinib and Tislelizumab in Patients With Locally Advanced Non-Small Cell Lung Cancer
NCT07086456 ·Status: RECRUITING ·Phase: PHASE2
-
Microtransplantation for Advanced and Relapsed Solid Tumors
NCT04937842 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Exploratory Study of Personalized mRNA Vaccine in Patients With Refractory Rhabdomyosarcoma
NCT06932861 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Under Whole-course of Immunotherapy, Gradient Fractionated RT with CCT Versus CFRT with CCT for LANPC Who Achieved PR Post Induction Chemotherapy.
NCT06675214 ·Status: RECRUITING ·Phase: PHASE3
-
Efficacy and Safety of a Third-Course of Neoadjuvant Immunochemotherapy Combined With SBRT in Locally Advanced Head and Neck Squamous Cell Carcinoma Patients With Stable Disease After Two Treatment Courses: A Single-Arm Exploratory Study
NCT06722495 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Study of Split-course Chemoradiotherapy For Locally Advanced None-small Cell Lung Cancer
NCT02573506 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
NCT04636762 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.
NCT05615142 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Local Non-salvage Radiotherapy for Synchronous Oligometastatic Non-small-cell Lung Cancer.
NCT03119519 ·Status: UNKNOWN ·Phase: PHASE2
-
Chemotherapy Combined With Radiotherapy vs Chemotherapy Alone for Distant Metastatic Nasopharyngeal Carcinoma
NCT02111460 ·Status: UNKNOWN ·Phase: PHASE3
-
Nab-TPC vs GP Combined With Camrelizumab in the Treatment of Recurrent/Metastatic Nasopharyngeal Carcinoma
NCT06669611 ·Status: RECRUITING ·Phase: PHASE3
-
A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors
NCT07105215 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Study of Tislelizumab for Locally Advanced Non-Small Cell Lung Cancer Following Neoadjuvant Chemotherapy Plus Tislelizumab ± Bevacizumab and Definitive Concurrent Chemoradiation Therapy
NCT05468242 ·Status: RECRUITING ·Phase: PHASE2
-
Retrospective Study in FFPE Samples From Younger Patients With Rhabdomyosarcoma
NCT06040229 ·Status: COMPLETED