Chemotherapy Combined With Radiotherapy vs Chemotherapy Alone for Distant Metastatic Nasopharyngeal Carcinoma
NCT02111460 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 126
Last updated 2020-05-08
Summary
This is a randomized parallel control trial to evaluate whether radical loco-regional Radiotherapy can prolong survival time of initial untreated metastatic nasopharyngeal carcinoma.
Conditions
- Nasopharyngeal Carcinoma
Interventions
- RADIATION
-
Loco-regional Radiotherapy
with or without Loco-regional Radiotherapy
Sponsors & Collaborators
-
First Affiliated Hospital, Sun Yat-Sen University
collaborator OTHER -
Guangdong Provincial People's Hospital
collaborator OTHER -
Sun Yat-sen University
lead OTHER
Principal Investigators
-
Ming y Chen, MD,Phd · Sun Yat-sen University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2013-10-31
- Primary Completion
- 2019-08-31
- Completion
- 2022-12-31
Countries
- China
Study Locations
More Related Trials
-
A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients
NCT04061278 ·Status: UNKNOWN ·Phase: PHASE3
-
Reducing Target Volumes in NPC Treated With Induction Chemotherapy Followed by Concurrent Chemoradiotherapy
NCT04384627 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Induction Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
NCT01245959 ·Status: UNKNOWN ·Phase: PHASE3
-
Reduced Volume of Neck Prophylactic Irradiation in Nasopharyngeal Carcinoma
NCT05780372 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Reduced vs Conventional Dosage Intensity-modulated Radiotherapy for Chemotherapy-sensitive Stage II-III Nasopharyngeal Carcinoma
NCT04448522 ·Status: RECRUITING ·Phase: PHASE3
-
The Role of Adding Concurrent Chemotherapy to IMRT in the Treatment of Stage II Nasopharyngeal Carcinoma
NCT02116231 ·Status: UNKNOWN ·Phase: PHASE2
-
Adjuvant Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
NCT00677118 ·Status: UNKNOWN ·Phase: PHASE3
-
Concurrent Chemotherapy in Intermediate Risk Patients Treated With Intensity-modulated Radiotherapy
NCT02289807 ·Status: WITHDRAWN ·Phase: NA
-
Induction Chemotherapy Followed by IMRT With or Without Concurrent Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma
NCT02434614 ·Status: UNKNOWN ·Phase: PHASE3
-
A Multicenter Trial Comparing Multi-course Chemotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma
NCT00705627 ·Status: UNKNOWN ·Phase: PHASE3
-
Surgery Alone Verus Sugery Combined with Dose-reduced Radiotherapy for Newly Diagnosed Stage I Nasopharyngeal Carcinoma
NCT06688760 ·Status: RECRUITING ·Phase: NA
-
Intensity-modulated Radiotherapy With or Without Concurrent Chemotherapy for Stage II Nasopharyngeal Carcinoma
NCT02610010 ·Status: RECRUITING ·Phase: PHASE3
-
Induction Gemcitabine and Cisplatin in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
NCT01872962 ·Status: UNKNOWN ·Phase: PHASE3
-
Reduced-dose Radiotherapy for Low-risk Stage III Patients With Nasopharyngeal Carcinoma
NCT03668730 ·Status: UNKNOWN ·Phase: PHASE2
-
Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma
NCT04522050 ·Status: UNKNOWN ·Phase: PHASE1
-
Combining RT With Immunotherapy and Chemotherapy in Metastatic Nasopharyngeal Carcinoma
NCT05385926 ·Status: RECRUITING ·Phase: PHASE2
-
Induction Chemotherapy Followed by Radiotherapy Alone or Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma
NCT03015727 ·Status: UNKNOWN ·Phase: PHASE3
-
Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy
NCT07328841 ·Status: RECRUITING ·Phase: PHASE3
-
Phase III Trial of Concurrent Chemotherapy Alone in Patients With Low-risk Nasopharyngeal Carcinoma
NCT05979961 ·Status: RECRUITING ·Phase: PHASE3
-
Nedaplatin in Treatment for Nasopharyngeal Carcinoma
NCT04834206 ·Status: COMPLETED ·Phase: PHASE2
-
Concurrent Docetaxel Plus Cisplatin or Cisplatin Alone With IMRT in High Risk Nasopharyngeal Carcinoma
NCT02610556 ·Status: UNKNOWN ·Phase: PHASE2
-
Comparing Chemotherapy With/Without Toripalimab For Primary Metastatic Nasopharyngeal Carcinoma
NCT04517214 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPC
NCT07332247 ·Status: RECRUITING ·Phase: PHASE2
-
SBRT and LDRT Combined With PD-1 Antibody and Chemotherapy in r/m Nasopharyngeal Carcinoma
NCT06323239 ·Status: RECRUITING ·Phase: PHASE2
-
ICCRT vs. CRT for Locally Advanced Nasopharyngeal Carcinoma
NCT05062005 ·Status: RECRUITING ·Phase: PHASE3