Implementation of Multiple Micronutrient Supplementation (MMS) for Pregnant Women in Uganda

Summary

The objective of this research is to understand how antenatal multiple micronutrient supplements (MMS) can be effectively implemented and scaled within the Uganda national health system context to support improved maternal nutrition and birth outcomes. Formative research has been conducted to design the implementation strategies that will be tested in this second phase of the study. The objectives are to:

* Describe the implementation of the MMS intervention (which consists of MMS product, a social behavior change communication (SBCC) strategy, capacity building, MMS supply chain support, monitoring, and evaluation) and explore acceptability, feasibility, fidelity, coverage, and potential for sustainability.
* Determine the effect of dispensing MMS in different bottle counts on MMS adherence and ANC attendance among pregnant women.
* Determine the cost and budget impact of MMS intervention implementation integrated in the Ugandan ANC service delivery system

Conditions

• Nutrient Deficiency

Interventions

DIETARY_SUPPLEMENT

Multiple Micronutrient Supplement (MMS) - dispensed in six 30-count bottles

MMS is a daily supplement provided to pregnant women. It will be delivered to pregnant women through the specified bottle-count protocol as designated by the 3 study arms. ANC providers will be trained to counsel pregnant women on using MMS using a novel job aid/adherence calendar.

DIETARY_SUPPLEMENT

Multiple Micronutrient Supplement (MMS) - dispensed in one 180-count bottle

MMS is a daily supplement provided to pregnant women. It will be delivered to pregnant women through the specified bottle-count protocol as designated by the 3 study arms. ANC providers will be trained to counsel pregnant women on using MMS using a novel job aid/adherence calendar.

DIETARY_SUPPLEMENT

Multiple Micronutrient Supplement (MMS) - dispensed in two 90-count bottles

MMS is a daily supplement provided to pregnant women. It will be delivered to pregnant women through the specified bottle-count protocol as designated by the 3 study arms. ANC providers will be trained to counsel pregnant women on using MMS using a novel job aid/adherence calendar.

Sponsors & Collaborators

• Vitamin Angels

  collaborator UNKNOWN

• UNICEF

  collaborator OTHER

• Child and Family Foundation of Uganda

  collaborator UNKNOWN

• Kirk Humanitarian

  collaborator UNKNOWN

• Johns Hopkins Bloomberg School of Public Health

  lead OTHER

Principal Investigators

• Monica Fox, MHS · Johns Hopkins University

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

0 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-06-18

Primary Completion

2026-06-30

Completion

2026-12-31

Countries

• Uganda

Study Locations