Effect of Finerenone in Patients With Non-diabetic Glomerulonephritis
NCT06835322 · Status: RECRUITING · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2025-03-26
Summary
This study aims to assess the effect of finerenone on proteinuria and GFR progression in patients with non-diabetic glomerulonephritis.
Conditions
Interventions
- DRUG
-
50 patients with biopsy proven glomerulonephritis who will receive 10 - 20 mg finerenone once daily orally in addition to their regular treatment protocol (RAAS blockers ± immunosuppression) for 6 months.
- DRUG
-
50 patients with biopsy proven glomerulonephritis who will receive placebo once daily in addition to their regular treatment protocol (RAAS blockers ± immunosuppression) for 6 months.
Sponsors & Collaborators
-
Alexandria University
lead OTHER
Principal Investigators
-
Mohamed Mamdouh Elsayed, MD · Associate professor
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-20
- Primary Completion
- 2025-08-20
- Completion
- 2025-09-10
Countries
- Egypt
Study Locations
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