Interleukin-17 (IL-17) Inhibitor in Combination With Tumor Necrosis Factor α (TNFα )Inhibitor for the Treatment of Ankylosing Spondylitis
NCT06833112 · Status: NOT_YET_RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2025-02-18
Summary
The aim of the study is to investigate the efficacy and safety of adalimumab in combination with secukinumab for the treatment of ankylosing spondylitis.
Conditions
Interventions
- DRUG
-
Secukinumab
The subjects were treated with secukinumab for 104 weeks. Secukinumab:150mg,q8w,subcutaneous injection.
- DRUG
-
The subjects were treated with adalimumab for 104 weeks. adalimumab: 40mg,q4w,subcutaneous injection.
Sponsors & Collaborators
-
The Affiliated Hospital Of Guizhou Medical University
lead OTHER
Principal Investigators
-
Jiashun Zeng, Medical Doctor · The Affiliated Hospital Of Guizhou Medical University
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-28
- Primary Completion
- 2027-08-31
- Completion
- 2028-02-29
- FDA Drug
- Yes
Countries
- China
Study Locations
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