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Comparison of Clomid and Lezra With Lezra for Ovulation Induction in Clomid Resistant PCOS Case

NCT06813118 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2026-05-07

No results posted yet for this study

Summary

Clomiphene citrate resistant i.e failure to ovulate after 6 cycles of ovulation induction effects 15-40% of patients with PCOS.Two treatment groups will be formed one recieving letrozole alone and another recieving CC and letrozole combined.Mature follicles and endometrial thickness will be checked by transvaginal ultrasound and results will be recorded.

Conditions

  • Polycystic Ovarian Syndrome

Interventions

DRUG

Clomiphene Citrate and letrozole

clomiphene citrate 100mg once daily along with letrozole 5mg to one group and letrozole 5mg to second group

Sponsors & Collaborators

  • HITEC-Institute of Medical Sciences

    lead OTHER

Principal Investigators

  • Rukhsana Shaheen Afzal, MBBS,FCPS · HITEC-Institute of Medical Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-06-07
Primary Completion
2025-03-25
Completion
2025-03-25

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06813118 on ClinicalTrials.gov