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Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

NCT06805253 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2025-06-11

No results posted yet for this study

Summary

Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.

Conditions

  • Aortic Valve Regurgitation
  • Mitral Valve Regurgitation
  • Left Ventricle Dilated
  • Left Atrium Dilated
  • Systolic Left Ventricular Heart Failure
  • Diastolic Heart Failure

Interventions

OTHER

Not applicable - observational study

observation only

Sponsors & Collaborators

  • Voronezh regional clinical hospital #1

    collaborator UNKNOWN

  • Petrovsky National Research Centre of Surgery

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-09
Primary Completion
2029-05-31
Completion
2030-05-31

Countries

  • Russia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06805253 on ClinicalTrials.gov