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DCN for ECD Livers

NCT06804746 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 143

Last updated 2026-01-27

No results posted yet for this study

Summary

The goal of this observational study is to learn whether extended criteria donor livers can be safely transplanted after sequential hypo- and normothermic machine perfusion in recipients requiring a liver transplant for end-stage liver disease, including a long-term follow-up. The main questions it aims to answer are:

* Death censored graft-survival
* Overall patient survival
* Frequency of frequent post-transplant complications (e.g. non-anastomotic biliary strictures)

Conditions

  • Liver Transplantation

Interventions

PROCEDURE

DHOPE-COR-NMP

Resuscitation and viability assessment through the previously published protocol of sequential hypo- and normothermic liver machine perfusion with controlled oxygenated rewarming (DHOPE-COR-NMP) based on a blood-based perfusate.

Sponsors & Collaborators

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-03-01
Primary Completion
2025-05-01
Completion
2025-10-31

Countries

  • Netherlands

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06804746 on ClinicalTrials.gov