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Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management

NCT06804434 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2025-02-03

No results posted yet for this study

Summary

This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.

Conditions

  • Pain
  • Anesthesia
  • Perioperative Care

Interventions

DRUG

Lidocaine Intravenous Infusion

intravenous lidocaine 10 mg/ml continuous infusion

DEVICE

NOL

Intraoperative Nociception Level index monitoring and guided analgesia

Sponsors & Collaborators

  • Osoian Cristiana

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-18
Primary Completion
2026-02-01
Completion
2026-02-01

Countries

  • Romania

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06804434 on ClinicalTrials.gov