PRogression of Atheroma Evaluated by CT Angiography and IntraCoronary Imaging tEchniques
NCT06794684 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50000
Last updated 2025-01-27
Summary
This is a combined cohort study with retrospectively and prospectively enrolled coronary artery disease (CAD) patients. All the patients will undergo clinical follow-up for up to 5 years, and repeat coronary CTA will be conducted after 2 years. Comprehensive morphological and functional plaque analysis will be performed. The impact of these morphological and functional parameters, alongside cardiometabolic factors and pharmacological treatments on plaque progression and the occurrence of major adverse cardiovascular events (MACEs) will be analyzed. In addition, intracoronary imaging techniques will be used to improve the accuracy of plaque analysis by coronary CTA.
Conditions
- Coronary Arterial Disease (CAD)
- Coronary Arteriosclerosis
Sponsors & Collaborators
-
Ruijin Hospital
lead OTHER
Principal Investigators
-
Ruiyan Zhang, M.D., Ph.D. · Ruijin Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-01
- Primary Completion
- 2027-05-31
- Completion
- 2030-05-31
Countries
- China
Study Locations
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