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Effects of Esketamine at Subanesthetic Dose on Emergence Delirium in Preschool Children Undergoing Ambulatory Laparoscopic Surgery

NCT06789185 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 96

Last updated 2025-05-22

No results posted yet for this study

Summary

Emergence delirium (ED) is a manifestation of acute postoperative brain dysfunction that occurs with a relatively high frequency after pediatric anesthesia. The incidence varies depending on the diagnostic criteria used and the combination of administered anesthetic drugs. The goal of this clinical trial is to investigate whether a subanesthetic dose of esketamine can reduce incidence of ED.

Conditions

  • Inguinal Hernia

Interventions

DRUG

0.1mg/kg esketamine

Intravenous injection 0.1mg/kg esketamine about 5min before the end of the surgery

DRUG

0.2mg/kg esketamine

Intravenous injection 0.2mg/kg esketamine about 5min before the end of the surgery

DRUG

0.1ml/kg normal saline

Intravenous injection 0.1ml/kg normal saline about 5min before the end of the surgery

Sponsors & Collaborators

  • Qiu jinpeng

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
24 Months
Max Age
71 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-07
Primary Completion
2025-05-16
Completion
2025-05-16

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06789185 on ClinicalTrials.gov