ARTLifeLine: Assisted Reproduction Technology (ART) Family Health and Development Trajectory Cohort (ARTLL)

Summary

The goal of this observational study is to study the health status of infertile couples and their offspring using assisted reproductive technologies. The main questions it aims to answer are:

1. On the basis of the assisted reproduction birth cohort and related research established by the team in the early stage, further expand the construction of the "tracking cohort of familial health and development using assisted reproduction", combine emerging technologies such as cross-database linking and integration, multi-omics sequencing and classical cohort research design, and carry out long-term longitudinal follow-up across generations, covering the whole life cycle and health in multi-dimension.
2. Build a disease risk prediction model for pregnant women and children with assisted reproduction.
3. Delineate the growth curve and neurobehavioral development trajectory of assisted reproductive offspring at different stages.
4. Evaluate the adolescent fertility potential and risk factors of assisted reproductive offspring.

Conditions

• Reproductive Techniques, Assisted
• Family
• Cohort Studies
• Development, Infant
• Reproductive Issues

Interventions

PROCEDURE

IVF treatment

Methods or procedures for the in vitro processing of human oocytes, sperm, or embryos for fertility purposes

Sponsors & Collaborators

• Peking University Third Hospital

  lead OTHER

Principal Investigators

• Jie Qiao, PhD · Peking University Third Hospital

• Rong Li, PhD · Peking University Third Hospital

• Wei Yuan, PhD · Peking University Third Hospital

• Tongyan Han, PhD · Peking University Third Hospital

• Liying Yan, PhD · Peking University Third Hospital

• Yuanyuan Wang, PhD · Peking University Third Hospital

• Rui / Yang, PhD · Peking University Third Hospital

• Xiaohui / Zhu, PhD · Peking University Third Hospital

• Lian / Chen, PhD · Peking University Third Hospital

• Meihua / Piao, PhD · Peking University Third Hospital

• Yunpu / Cui, PhD · Peking University Third Hospital

• Yanan / Tang, PhD · Peking University Third Hospital

• Chunling / Huang, PhD · Peking University Third Hospital

• Chunmei / Zhang, PhD · Peking University Third Hospital

• Linlin / Wang, PhD · Peking University Third Hospital

• Ningning / Pan, PhD · Peking University Third Hospital

• Huifeng Shi, PhD · Peking University Third Hospital

• Tianchen / Wu, PhD · Peking University Third Hospital

• Wanning / Qiu, PhD · Peking University Third Hospital

• Jinfang / Yuan, PhD · Peking University Third Hospital

• Hui / Zhang, MD · Peking University Third Hospital

• Qingqing Wang · Peking University Third Hospital

• Meng Qin · Peking University Third Hospital

• Ying Kuo · Peking University Third Hospital

• Wenxi Zhang · Peking University Third Hospital

• Shuo Guan · Peking University Third Hospital

• Siming Jiang · Peking University Third Hospital

• Fei Kong · Peking University Third Hospital

• Tian Tian, PhD · Peking University Third Hospital

• Lixue Chen · Peking University Third Hospital

• Yu Fu · Peking University Third Hospital

• Fang Liu · Peking University Third Hospital

Eligibility

Min Age

0 Years

Max Age

50 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-01-20

Primary Completion

2043-12-31

Completion

2043-12-31

Countries

• China

Study Locations