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Clinical Impact of Non-invasive Neurally Adjusted Ventilatory Assist in Very Preterm Infants

NCT06786039 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2025-06-17

No results posted yet for this study

Summary

This is a prospective observational study investigating the impact of NIV-NAVA on short-term clinical outcomes and long-term neurodevelopment in very preterm infants.

Conditions

  • Preterm Infant

Interventions

PROCEDURE

Non-invasive NAVA

Initiate respiratory assist with NIV-NAVA within 48 hours. The setting of respiratory support will be adjusted based on clinical conditions of each subject. NIV-NAVA could be switched to nasal continuous airway pressure or high flow nasal cannula, and it also could be stopped after initial stabilization. In cases of respiratory distress syndrome, lung surfactant will be administered via the less invasive surfactant administration (LISA) method and avoid endotracheal intubation whenever possible. For who intubated in the delivery room, extubation with NIV-NAVA should be considered as soon as possible. Endotracheal intubation with invasive ventilation could be applied when clinical deteriorations happens.

Sponsors & Collaborators

  • Korea University Anam Hospital

    lead OTHER

Eligibility

Min Age
1 Hour
Max Age
48 Hours
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-20
Primary Completion
2029-12-20
Completion
2030-12-20

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06786039 on ClinicalTrials.gov