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Ventilator Weaning Outcome Between NIV-NAVA and Nasal CPAP (or IMV ) Modes in Premature Neonates

NCT04118400 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2020-03-12

No results posted yet for this study

Summary

Premature neonates are prone to respiratory distress and need ventilator support because of the rapid breathing and large variations in respiratory patterns. The setting and adjustment of the ventilator for premature neonate is not easy, often resulting in poor patient-ventilator interaction, increased work of breathing, patient discomfort and delayed weaning . Recently, a new ventilation mode (NAVA; Neurally Adjusted Ventilatory Assist) mode, allows the respirator to provide a proportional ventilation mode based on the patients' diaphragm electrical activity, which was validated in many domestic and international clinical researches. The NAVA mode improves patient-ventilator interaction, reduces work of breathing and contributes to early weaning and extubation . When participating in this study, the neonate with receive a special oral tube placement, which is used to replace the original gastric tube to monitor the electrical activity of the diaphragm.

Conditions

  • Respiratory Distress Syndrome in Premature Infant

Interventions

PROCEDURE

NIV-NAVA

NAVA mode during Non-invasive ventilation

PROCEDURE

Nasal CPAP or NIMV mode

Nasal CPAP or NIMV mode during Non-invasive ventilation

Sponsors & Collaborators

  • Taipei Medical University Hospital

    lead OTHER

Principal Investigators

  • Hsin-yu LI · Taipei Medical University Hospital, Taiwan, R.O.C

Eligibility

Min Age
30 Weeks
Max Age
37 Weeks
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-10-31
Primary Completion
2020-10-06
Completion
2021-08-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04118400 on ClinicalTrials.gov