Digital Strategies to Advance Help-Seeking - Aim 3

Summary

This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeking subtypes in 25,000 youth who screen positive for psychosis-risk on Mental Health America's national online screening platform, iteratively develop and test theory and data-driven, personalized strategies to advance help-seeking using Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial, identify the most accurate CHR screening threshold in an online environment, and link youth, when indicated, to local clinical care via AMP-SCZ, a NIH funded national network of CHR programs throughout the US. This academic-industry partnership aims to curate one of the largest datasets of youth with CHR, and to develop effective strategies to enhance early help-seeking, in a population where help-seeking is critical and a significant barrier to care.

Conditions

• Clinical High Risk
• Early Psychosis
• First Episode Psychosis

Interventions

OTHER

Digital nudge

Digital help seeking advancement strategies over text and online.

Sponsors & Collaborators

• University of California, San Francisco

  collaborator OTHER

• University of California, Davis

  collaborator OTHER

• Mental Health America

  collaborator OTHER

• University of Washington

  collaborator OTHER

• Strong365

  collaborator UNKNOWN

• National Institute of Mental Health (NIMH)

  collaborator NIH

• Columbia University

  lead OTHER

Principal Investigators

• Michael Birnbaum, MD · Columbia University

Study Design

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

NONE

Model

SEQUENTIAL

Eligibility

Min Age

12 Years

Max Age

29 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-02-02

Primary Completion

2028-05-31

Completion

2028-05-31

Countries

• United States

Study Locations