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Fluid Responsiveness and Venous Congestion Evolution During Volume Expansion

NCT06772038 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 64

Last updated 2025-01-13

No results posted yet for this study

Summary

Fluid responsiveness is a critical determinant guiding fluid therapy in critically ill patients. However, excessive fluid administration can result in fluid overload, leading to venous congestion and worse clinical outcomes. Venous congestion, a marker of impaired fluid clearance, is increasingly recognized as a significant contributor to poor prognosis. Previous studies have demonstrated the coexistence of fluid responsiveness and venous congestion in critically ill patients. Notably, these studies were limited by the absence of fluid challenge-the gold standard for assessing fluid responsiveness-leaving the dynamic relationship between fluid responsiveness and venous congestion incompletely understood. This study aims to investigate the interplay and temporal evolution of fluid responsiveness and venous congestion following a standardized fluid challenge in critically ill patients.

Conditions

  • Hemodynamic
  • Fluid Responsiveness
  • Venous Congestion
  • Fluid Challenge

Sponsors & Collaborators

  • First Affiliated Hospital, Sun Yat-Sen University

    collaborator OTHER

  • Longgang District People's Hospital of Shenzhen

    collaborator OTHER

  • Bicetre Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-05
Primary Completion
2025-06-30
Completion
2025-07-30

Countries

  • China
  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06772038 on ClinicalTrials.gov