Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation
NCT06763081 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 160
Last updated 2025-09-08
Summary
The purpose of this study is to identify and validate a panel of genetic markers associated with selective serotonin reuptake inhibitors (SSRI)-induced behavioural activation in children and youth with major depressive disorder (MDD), anxiety disorders, or obsessive-compulsive disorder (OCD) that could be used clinically to reduce the incidence of this adverse event and improve health outcomes.
Conditions
- Behavioral Activation
- Major Depressive Disorder
- Anxiety Disorders
- Antidepressant Drug Adverse Reaction
- Obsessive Compulsive Disorder (OCD)
- Major Depression
Interventions
- OTHER
-
Not applicable- observational study
It's an observational study. Participants are not assigned an intervention as part of the study.
Sponsors & Collaborators
-
Health Sciences Centre Foundation, Manitoba
collaborator OTHER -
Children's Hospital Research Institute of Manitoba
collaborator OTHER -
University of Calgary Cumming School of Medicine
collaborator UNKNOWN -
University of Manitoba
lead OTHER
Eligibility
- Min Age
- 6 Years
- Max Age
- 24 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-03-01
- Primary Completion
- 2028-12-31
- Completion
- 2030-12-31
Countries
- Canada
Study Locations
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