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Efficacy of Diosmin and Hesperidin on Early Rehabilitation After Total Knee Arthroplasty

NCT06753448 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 190

Last updated 2025-07-15

No results posted yet for this study

Summary

The goal of this clinical trial is to find out the efficacy of diosmin and hesperidin on postoperative early rehabilitation after primary total knee arthroplasty. The main questions it aims to answer are:

Does diosmin and hesperidin combined drug decreases the lower extremity swelling, pain and increases the range of motion after primary total knee arthroplasty surgery compared to standard therapy group? Does diosmin and hesperidin combined drug decreases inflammation after total knee arthroplasty surgery.

Participants will take diosmin and hesperidin in addition to standard therapy for 14 days after total knee arthroplasty surgery. Lower extremity swelling, pain and range of motion of the patients will be recorded in every visit.

Conditions

  • Total Knee Arthroplasty
  • Venous Insufficiency of Leg

Interventions

DRUG

Diosmin and Hesperidin Combination

Participants will take diosmin and hesperidin combination for 14 days after total knee replacement surgery.

Sponsors & Collaborators

  • Ankara Etlik City Hospital

    lead OTHER_GOV

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-08
Primary Completion
2025-06-10
Completion
2025-06-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06753448 on ClinicalTrials.gov