Tapering Heart Failure Medication in Patients With Heart Failure With Recovered Ejection Fraction; Open Label Prospective Random Trial
NCT06724653 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2026-03-27
Summary
Study start date is on Nov 27th 2024.
A patient with an initial ejection fraction (EF) of less than 40%, whose follow-up shows an improvement to an EF of 50% or higher, along with the left ventricular end-diastolic diameter returning to the normal range and taking 3 more heart failure medication randomed to drug tapering group ( RAS blocker or beta blocker) or continuing medication group.
Conditions
- Heart Failure
- Ejection Fraction
- Recovery of Function
Interventions
- DRUG
-
RAS blocker tapering group
RAS blocker tapering out
- DRUG
-
Beta blocker tapering out
Beta blocker tapering out group
Sponsors & Collaborators
-
Chungnam National University Hospital
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-03-06
- Primary Completion
- 2025-05-26
- Completion
- 2027-11-26
Countries
- South Korea
Study Locations
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