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Definition of Acute Kidney Injury by Urine Output in Critically Ill Patients

NCT06722924 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 15000

Last updated 2024-12-09

No results posted yet for this study

Summary

The goal of this observational study is to explore the association between urine output and acute kidney injury in severely ill patients admitted to intensive care units. The main research questions are:

What is the optimal threshold for defining reduced urine output in critically ill patients in intensive care? Is this threshold the same for different outcomes such as acute kidney injury, chronic kidney dysfunction, or mortality? Does this threshold change with treatment involving diuretics or dialysis? Does the patient's fluid balance or the amount of administered fluid affect the association between reduced urine output and the outcomes mentioned above? Is the optimal threshold for defining reduced urine output different for various patient categories and diagnoses, such as sepsis, burn injuries, or ARDS? Are there differences between surgical and non-surgical patients regarding the optimal threshold for defining reduced urine output in intensive care? Does the patient's comorbidity influence the level of reduced urine output that should be considered pathological?

Conditions

  • Acute Kidney Injury
  • Critical Illness
  • Critical Care, Intensive Care
  • Critical Care, Fluid Resuscitation

Sponsors & Collaborators

  • Uppsala University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-31
Primary Completion
2025-01-31
Completion
2025-03-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06722924 on ClinicalTrials.gov