Semmelweis Esophageal Cancer Study: Noninvasive Prognostic Parameters in Patients With Oesophageal and Esophagogastric Junction Cancer
NCT06713993 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2026-04-24
Summary
The objective of this observational study was to gain a deeper understanding of the epidemiology of the disease in Hungary through a broad analysis of patients with new-onset esophageal-oesophageal-stomach junction tumors, and to identify key parameters that could potentially influence the outcome of the disease and are closely correlated with morbidity and mortality. The investigators' primary objective is to identify potential factors and conditions that could be influenced and modified to enhance the disease outcome.
Main questions:
1. What are the measurable changes in performance, workload, nutritional status, cardiac function, mental status in the patients studied?
2. What is the time course of the changes during and after treatment?
3. Which pathological parameters are associated with disease outcome and which are potential points of intervention to improve the course of the disease?
Patients will undergo a detailed physical and nutritional assessment, non-invasive imaging tests and several questionnaires in addition to the usual pre- and post-operative examinations.
Conditions
- Esophageal Cancer (EsC)
Sponsors & Collaborators
-
Semmelweis University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-09-10
- Primary Completion
- 2029-09-30
- Completion
- 2034-09-10
Countries
- Hungary
Study Locations
More Related Trials
-
Detection of (Sub)Clinical Toxicity in Irradiated vs. Non-irradiated Surgically Treated Esophageal Cancer Patients: a Pilot Study (CROSS SECT)
NCT03396614 ·Status: COMPLETED
-
Quality of Life Outcomes Following Minimally Invasive and Open Esophagectomy for Esophageal Cancer
NCT01558648 ·Status: COMPLETED
-
CIRCULATing Biomarkers for Individualized Surgical Therapy in gastroEsophageal Cancer - Phase 1
NCT04455282 ·Status: RECRUITING
-
OPPOSITE: Outcome Prediction of Systemic Treatment in Esophagogastric Carcinoma
NCT03429816 ·Status: COMPLETED ·Phase: NA
-
Quality-of-Life Assessment of Patients Who Have Cancer of the Esophagus
NCT00003321 ·Status: COMPLETED
-
Retrospective Review of Esophageal Cancer at MSKCC
NCT05706558 ·Status: RECRUITING
-
Selective Dose Escalation for Esophageal Cancer
NCT00139633 ·Status: UNKNOWN ·Phase: PHASE2
-
Circulating Tumor Cells as a Biomarker for Preoperative Prognostic Staging in Patients With Esophageal Cancer
NCT01858805 ·Status: COMPLETED
-
Combination Chemotherapy and Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
NCT00381706 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Chemoimmunotherapy Followed by Surgery and Postoperative Radioimmunotherapy
NCT06602843 ·Status: RECRUITING ·Phase: NA
-
Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC
NCT06601309 ·Status: RECRUITING ·Phase: PHASE2
-
S0415 Cetuximab in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer
NCT00096031 ·Status: COMPLETED ·Phase: PHASE2
-
Esophageal Squamous Cell Cancer Surveillance With Cytosponge
NCT04192695 ·Status: COMPLETED ·Phase: NA
-
Biological Factors in Predicting Response to Treatment in Patients With Esophageal Cancer or Rectal Cancer
NCT00628368 ·Status: COMPLETED ·Phase: NA
-
Biomarkers and Functional Imaging in Predicting Response of Esophageal Cancer
NCT03029793 ·Status: UNKNOWN
-
Neoadjuvant Immunotherapy (PD-1 / PD-L1) Combined With Chemotherapy for Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma: a Single Center, Prospective, Open, One Arm Exploratory Clinical Study
NCT05028231 ·Status: UNKNOWN
-
Prognostic Analysis of Esophageal Cancer with Complete Pathological Response After Neoadjuvant Therapy
NCT06889402 ·Status: NOT_YET_RECRUITING
-
Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant or Definitive Chemoradiation in Patients With Esophageal Cancer
NCT03712774 ·Status: RECRUITING
-
Registry for Esophageal and Gastroesophageal Junction Cancer
NCT06558786 ·Status: RECRUITING
-
Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer
NCT00551759 ·Status: TERMINATED ·Phase: PHASE2
-
Fraction Dose Escalation of Split-course Hypofractionated Concurrent Chemoradiotherapy Following Induction Chemo-immunotherapy in Unresectable Locally Advanced Esophageal Squamous Carcinoma: a Phase I Study.
NCT06020885 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Postoperative Immune Maintenance Therapy for Esophageal Squamous Cell Carcinoma After Radical Resection
NCT06161909 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Cetuximab and Radiation Therapy for Surgically Resectable Esophageal and Gastroesophageal (GE) Junction Carcinomas
NCT00319735 ·Status: COMPLETED ·Phase: PHASE2
-
Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma
NCT05740995 ·Status: RECRUITING
-
Comparison of Systematic Surgery Versus Surveillance and Rescue Surgery in Operable Oesophageal Cancer With a Complete Clinical Response to Radiochemotherapy
NCT02551458 ·Status: TERMINATED ·Phase: PHASE2/PHASE3