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Biomarkers and Functional Imaging in Predicting Response of Esophageal Cancer

NCT03029793 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2017-01-24

No results posted yet for this study

Summary

The purpose of this study is to determine whether combination of molecular and biomarkers with functional imaging can predict pathologic response and clinical outcomes in squamous esophageal cancer patients who undergo trimodality therapy which includes neoadjuvant chemoradiotherapy and surgery

Conditions

  • Esophageal Cancer

Interventions

OTHER

Biomarkers Testing

CRT resistance biomarkers will be detected before CRT, 2-3 weeks after the initiation of CRT, and 4 weeks post-CRT.

OTHER

Functional Imaging analysis

The SUV value and texture parameters of 18F-FDG PET-CT as well as ADC values DWI-MRI will be measures before CRT, 2-3 weeks after the initiation of CRT, and 4 weeks post-CRT.

Sponsors & Collaborators

  • Air Force Military Medical University, China

    lead OTHER

Principal Investigators

  • Mei Shi, MD · Department of Radiation Oncology, Xijing Hospital, Fourth Military Medical University

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2019-01-31
Completion
2020-01-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03029793 on ClinicalTrials.gov