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Active MMP-8 in Oral Fluid for the Detection of Oral and Oropharyngeal Cancer

NCT06701058 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 107

Last updated 2024-11-22

No results posted yet for this study

Summary

The goal of this observational study is to evaluate whether the active-matrix metalloproteinase-8 (aMMP-8) mouth-rinse test can help detect oral and oropharyngeal cancers. Researchers measured aMMP-8 levels in mouth-rinse samples collected from 77 cancer participants and 50 non-cancer participants in a clinical setting.

The main question this study seeks to answer:

Can the aMMP-8 mouth-rinse test accurately identify and differentiate cancer participants from non-cancer participants in real-time?

Conditions

  • Oropharyngeal Cancers
  • Biomarker in Early Diagnosis
  • Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer
  • Periodontal Diseases

Sponsors & Collaborators

  • Karolinska Institutet

    collaborator OTHER

  • University of Helsinki

    collaborator OTHER

  • Helsinki University Central Hospital

    lead OTHER

Principal Investigators

  • Antti Mäkitie, Prof. · Helsinki University Central Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-28
Primary Completion
2024-09-01
Completion
2024-09-18

Countries

  • Finland

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06701058 on ClinicalTrials.gov