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Thrombosis in Diffuse Large B-cell Lymphoma:the PREDIC-TO (PREDICt ThrOmbosis) Study

NCT06694779 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2024-11-19

No results posted yet for this study

Summary

Comparative Evaluation of Thrombotic Risk Models in DLBCL patients

Objective: To assess the impact of thrombotic risk factors and compare the performance of existing predictive models (Khorana, Throly, Model IX) in Diffuse Large B-cell Lymphoma (DLBCL)

Primary Endpoints:

Measure thrombotic risk factors in existing models Determine occurrence, type, and timing of venous thrombotic events

Secondary Endpoints:

Assess performance of models in patients without thrombotic events at diagnosis Evaluate dynamic risk factors during DLBCL treatment Identify additional risk factors not included in published models Analyze overall survival and VTE-free survival

Methodology:

Real-world cohort study of DLBCL patients Collection of static and dynamic risk factors Correlation analysis of risk factors with thrombotic events Development and validation of DLBCL-specific predictive model

Conclusion:

This study aims to compare existing predictive models and develop a DLBCL-specific model to aid in identifying high-risk patients and inform thromboprophylaxis decisions. Results will contribute to improved understanding and management of thrombotic risk in DLBCL.

Conditions

Sponsors & Collaborators

  • University of Milano Bicocca

    collaborator OTHER

  • Fondazione IRCCS San Gerardo dei Tintori

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-25
Primary Completion
2025-05-25
Completion
2026-05-25

Countries

  • Italy

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06694779 on ClinicalTrials.gov