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Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease

NCT06688968 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 120

Last updated 2025-03-19

No results posted yet for this study

Summary

The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and control subjects.

The main questions it aims to answer are:

1. The description of different profiles of musical engagement in early-stage AD, in PD and in healthy elderly subjects.
2. The extent of executive, mnestic and hedonic dysfunctions will impact differently on emotional engagement, autobiographical evocation and sensitivity to musical reward, and will therefore enable distinct profiles to be drawn up.

Participants will have an intervention consisting of an interview with a neuropsychologist lasting approximately 2 hours, including :

* A semi-structured interview to check the participants eligibility and gather demographic data.
* Neuropsychological tests and questionnaires will then be administered.
* A relative of the study participant will help complete questionnaires.

Conditions

  • Alzheimer Disease, Early Onset
  • Parkinsons Disease with Dementia
  • Non Pharmacological Intervention

Interventions

BEHAVIORAL

neuropsychologist interview

It will take place either at the hospital or at the participant's home. This interview will consist of : * socio-demographic data collection * neuropsychological tests: * MMSE test (Mini Mental State Examination) cognitive function * RL-RI-16 test (16-item free recall/indexed recall test) * BECS test (Semantic knowledge assessment battery ) * WCST test (Wisconsin Card Sorting Test ) * Musical Cognition Test * Help from the participant's relative to answer certain questions, in particular the MuseEQ-24 questionnaire

BEHAVIORAL

questionnaire

The participant answers questionnaires: * Questionnaire MusEQ-24 self reported (Music Engagement Questionnaire) * Questionnaire BMRQ (Barcelona Reward Music Questionnaire) * Questionnaire SHAPS (Snaith-Hamilton Pleasure Scale) * Questionnaire LARS (Lille's Apathy Rating Scale) * Questionnaire PHQ-9 (Patient Health Questionnaire 9 items)

Sponsors & Collaborators

  • Laboratoire EPSYLON

    collaborator UNKNOWN

  • University Hospital, Montpellier

    lead OTHER

Principal Investigators

  • KARIM BENNYS, MD · University Hospital, Montpellier

Study Design

Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-02-04
Primary Completion
2025-12-01
Completion
2025-12-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06688968 on ClinicalTrials.gov