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Endoscopy and Primary Sclerosing Cholangitis

NCT06686810 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 118

Last updated 2024-11-14

No results posted yet for this study

Summary

Primary Sclerosing Cholangitis (PSC) is a chronic, cholestatic, immune-mediated liver disease characterized by segmental inflammation, fibrosis and destruction of the intra and / or extrahepatic biliary tree.

Patients suffering from PSC can develop biliary strictures and symptoms (jaundice, itching, cholangitis) requiring endoscopic therapy by Endoscopic Retrograde Cholangiopancreatography (ERCP).

ERCP can play an important role in symptoms control, cholangiocarcinoma diagnosis.

PSC can lead to liver failure and subsequent need for liver transplantation, ERCP can therefore delay the time for liver transplantation.

With this work the investigators want to report our thirty years of experience in the endoscopic treatment of PSC.

Conditions

  • Primary Sclerosing Cholangitis (PSC)

Interventions

PROCEDURE

Endoscopic Retrogradade CholangioPancreatography (ERCP)

ERCP is an endoscopic therapeutic procedure to drain the bile ducts in case of stones or biliary strictures that can be treated by balloon dilatation or stents (plastic or metal) insertion

Sponsors & Collaborators

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS

    lead OTHER

Principal Investigators

  • Andrea Tringali, MD, PhD · Fondazione Policlinico A. Gemelli IRCCS Roma, Italy

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2024-11-04
Completion
2024-11-04

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06686810 on ClinicalTrials.gov