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Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia

NCT06684275 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2024-12-31

No results posted yet for this study

Summary

The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults.

The main questions it aims to answer are:

* Does PRF or PRF + TRF provide better pain relief for patients with trigeminal neuralgia?
* What is the safety profile and complication rate of PRF versus PRF + TRF?

Researchers will compare the effects of PRF and PRF + TRF to see if thermal lesioning in addition to pulsed RF provides superior long-term pain relief and reduces the need for analgesic medication.

Participants will:

* Undergo either PRF or PRF + TRF treatment targeting the trigeminal nerve.
* Be assessed for pain relief, functional status, and adverse events over a 3-month follow-up period.

Conditions

  • Trigeminal Neuralgia

Interventions

PROCEDURE

Pulsed Radiofrequency (PRF)

Participants will receive pulsed radiofrequency (PRF) treatment targeting the trigeminal nerve to manage pain associated with trigeminal neuralgia. This non-ablative technique uses electrical pulses to modulate nerve function, aiming to provide pain relief without creating a thermal lesion.

PROCEDURE

Pulsed and Thermal Radiofrequency (PRF + TRF)

Participants will receive a combination of pulsed radiofrequency (PRF) and thermal radiofrequency (TRF) treatments targeting the trigeminal nerve. This approach combines the non-ablative effects of PRF with the thermal lesioning of TRF to provide long-term pain relief for trigeminal neuralgia.

Sponsors & Collaborators

  • Zagazig University

    lead OTHER_GOV

Principal Investigators

  • Ahmed A Bessar, MD, PhD · Assistant Professor of Diagnostic and Interventional Radiology, Zagazig Uni.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-10
Primary Completion
2025-03-10
Completion
2025-04-10

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06684275 on ClinicalTrials.gov