Cohort-Based Study of Diagnostic Biomarkers for Neurosyphilis
NCT06680011 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 360
Last updated 2024-11-08
Summary
The goal of this observational study is to identify diagnostic biomarkers for neurosyphilis in patients with the condition. The main questions it aims to answer are:
What plasma biomarkers are associated with neurosyphilis? What electrophysiological characteristics (EEG and eye movement) are linked to neurosyphilis? Researchers will compare biomarker data from plasma and gut microbiome analyses with electrophysiological findings to see if these factors can help diagnose neurosyphilis.
Participants will:
Provide clinical information such as age, gender, symptoms, and disease course Submit blood and urine samples for proteomics and metagenomic sequencing Undergo EEG and eye movement evaluations for electrophysiological analysis
Conditions
- Neurosyphilis
- Biomarkers
- Proteomics
Sponsors & Collaborators
-
Shanghai Mental Health Center
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-04-01
- Primary Completion
- 2025-12-31
- Completion
- 2026-06-30
Countries
- China
Study Locations
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