A Phase 1 Study to Examine the Effects of Itraconazole After Single Dose Administration of Varegacestat (AL102) to Healthy Participants
NCT06677996 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 22
Last updated 2025-05-11
Summary
This is an open label, fixed sequence, 1-way crossover drug-drug interaction (DDI) study in healthy participants.
Conditions
- Healthy Volunteer
Interventions
- DRUG
-
varegacestat
Experimental intervention
- DRUG
-
Itraconazole (200 mg)
Intervention to evaluate DDI with experimental intervention
Sponsors & Collaborators
-
Immunome, Inc.
lead INDUSTRY
Principal Investigators
-
Michelle Valentine · Celerion
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-11-11
- Primary Completion
- 2024-12-30
- Completion
- 2025-05-07
- FDA Drug
- Yes
Countries
- United States
Study Locations
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