A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis
NCT00002159 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2005-06-24
Summary
To assess the safety of intravenous itraconazole compared to amphotericin B in HIV positive or negative persons with blastomycosis or histoplasmosis.
Conditions
- HIV Infections
- Histoplasmosis
- Blastomycosis
Interventions
- DRUG
-
Itraconazole
- DRUG
-
Amphotericin B
Sponsors & Collaborators
-
Janssen, LP
lead INDUSTRY
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 13 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
More Related Trials
-
A Study of Treatments for Fungal Infections of the Mouth and Throat in HIV-Infected Patients Who Have Had Success With Itraconazole But Not With Fluconazole
NCT00002341 ·Status: COMPLETED ·Phase: NA
-
Study of Micafungin in Patients With Invasive Candidiasis or Candidemia
NCT00105144 ·Status: COMPLETED ·Phase: PHASE3
-
Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis.
NCT00002132 ·Status: COMPLETED ·Phase: NA
-
Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)
NCT04218851 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy
NCT02895529 ·Status: TERMINATED ·Phase: PHASE4
-
Trial of Micafungin (FK463) in Combination With Liposomal Amphotericin B (AmBisome) for Aspergillosis
NCT00047827 ·Status: TERMINATED ·Phase: PHASE2
-
Chronic Pulmonary Aspergillosis and Ambisome Aerosol with Itraconazole
NCT03656081 ·Status: RECRUITING ·Phase: PHASE3
-
Endemic Mycoses Treatment With SUBA-itraconazole vs Itraconazole
NCT03572049 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Micafungin Salvage Mono-therapy in Invasive Aspergillosis
NCT00376337 ·Status: TERMINATED ·Phase: PHASE2
-
An Efficacy and Safety Study of Itraconazole Sequential Therapy (Intravenous Injection Followed by Oral Solution) in Invasive Pulmonary Fungal Infections
NCT01823289 ·Status: COMPLETED ·Phase: PHASE4
-
Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and Sporotrichosis
NCT00004808 ·Status: COMPLETED ·Phase: PHASE2
-
A Comparison of Fluconazole and Amphotericin B in the Treatment of Fungal Infections
NCT00002277 ·Status: COMPLETED ·Phase: PHASE3
-
Comparative Study of Micafungin (FK463) Versus Placebo as Prophylactic Antifungal Therapy in the ICU
NCT00048750 ·Status: TERMINATED ·Phase: PHASE3
-
Multicenter Comparison of Fluconazole (UK-49,858) and Amphotericin B as Maintenance Treatment for the Prevention of Relapse of Cryptococcal Meningitis in Patients With Acquired Immunodeficiency Syndrome
NCT00002074 ·Status: COMPLETED ·Phase: NA
-
A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants
NCT06421714 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)
NCT01782131 ·Status: COMPLETED ·Phase: PHASE3
-
Histoplasmosis Induction and Consolidation Therapy Factorial Randomized Clinical Trial (Histo-FACT)
NCT07261150 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Itraconazole Therapy In Bronchiectasis With Airway Mold
NCT07283497 ·Status: RECRUITING ·Phase: PHASE4
-
A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis
NCT00000639 ·Status: COMPLETED ·Phase: NA
-
A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male Subjects
NCT05549531 ·Status: COMPLETED ·Phase: PHASE1
-
Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections
NCT00413218 ·Status: COMPLETED ·Phase: PHASE3
-
Pilot Study to Determine the Feasibility of Fluconazole for Induction Treatment and Suppression of Relapse of Histoplasmosis in Patients With the Acquired Immunodeficiency Syndrome
NCT00000627 ·Status: COMPLETED ·Phase: NA
-
Micafungin Versus Intravenous Itraconazole as Empirical Antifungal Therapy for Febrile Neutropenic Patients With Hematological Diseases
NCT01344681 ·Status: COMPLETED ·Phase: PHASE2
-
Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS
NCT00001017 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants
NCT03816176 ·Status: COMPLETED ·Phase: PHASE2