Autologous CAR-T Cells (WD-01) for Metastatic Colorectal Cancer
NCT06675513 · Status: SUSPENDED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2026-05-07
Summary
This is an investigator initiated trial to assess the efficacy and safety of a GCC-targeting CAR-T therapy (WD-01) in the metastatic colorectal cancer.
Conditions
- CRC (Colorectal Cancer)
- Metastatic Colorectal Cancer
Interventions
- BIOLOGICAL
-
An armored GCC targeting WD-01 CAR-T to treat cancer patients Other Name:
Autologous WD-01 CAR-T therapy with Wondercel's "Warrior" armor strategy will be explored for its advantage over other armor platforms.
Sponsors & Collaborators
-
Wondercel Biotech (ShenZhen)
lead INDUSTRY
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-05-18
- Primary Completion
- 2027-12-30
- Completion
- 2029-12-30
Countries
- China
Study Locations
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