Cold Therapy in the Treatment of Exercise-induced Muscle Damage
NCT02341612 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 65
Last updated 2015-01-19
Summary
Subjects were randomly placed in five groups: (1) single exposure at 5°C in cold water immersion, (2) single exposure at 15°C in cold water immersion, (3) multiple exposures at 10°C in cold water immersion, (4) whole body cryotherapy (WBC) at 110°C and (5) passive recovery (control group). The single exposure groups performed cold water immersion immediately after exercise-induced muscle damage (EIMD) for 20 minutes. The multiple exposures group performed cold water immersion immediately, 24h, 48h and 72h after EIMD (once a day) for 20 minutes. The WBC group remained in the cabin immediately after EIMD for 3 min. The control group was not exposed to treatment after the EIMD protocol. The subjects were asked to visit the laboratory on seven occasions. The first visit was the familiarization of the subjects with experimental procedures and their anthropometric assessment. One week after familiarization, on visit two, volunteers performed the exercise-induced muscle damage (EIMD) protocol and they were allocated to one of experimental groups. Indirect markers of muscle damage and inflammatory responses were evaluated at baseline (pre), immediately post, 24h, 48h, 72h, 96h, and 168h following the EIMD protocol by measuring anterior thigh muscle swelling, isometric knee extensors peak torque, knee extensors muscle soreness, countermovement vertical jump and blood sample analyzes.
Conditions
- Cryotherapy Effect
Interventions
- OTHER
-
single exposure at 5°C in CWI
The subjects of this group performed cold water immersion immediately after exercise-induced muscle damage (EIMD) a single exposure at 5°C for 20 minutes.
- OTHER
-
single exposure at 15°C in CWI
The subjects of this group performed CWI immediately after EIMD a single exposure at 15°C for 20 minutes.
- OTHER
-
multiple exposures at 10°C in CWI
The subjects of this group performed CWI immediately, 24h, 48h and 72h after EIMD (once a day) for 20 minutes.
- OTHER
-
whole body cryotherapy (WBC)
The whole body criotherapy (WBC) group remained in the cabin immediately after EIMD for 3 minutes.
- OTHER
-
passive recovery
The control group was exposed to treatment after the EIMD protocol.
Sponsors & Collaborators
-
Conselho Nacional de Desenvolvimento Científico e Tecnológico
collaborator OTHER_GOV -
University of Brasilia
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2013-12-31
- Primary Completion
- 2014-08-31
- Completion
- 2014-08-31
Countries
- Brazil
Study Locations
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