MedTrace Logo

Liposomal Bupivacaine and Bupivacaine for TTMPB in Median Sternotomy

NCT06646172 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 38

Last updated 2024-10-28

No results posted yet for this study

Summary

In light of the ongoing controversy surrounding the efficacy of bupivacaine liposomes, our study was designed to investigate, for the first time, the differential postoperative analgesic effects between bupivacaine liposomes combined with bupivacaine hydrochloride and bupivacaine hydrochloride alone in transverse thoracic muscle plane block treatment. The aim is to provide evidence-based medical guidance for drug selection in regional block local anesthesia.

Conditions

  • Median Sternotomy

Interventions

PROCEDURE

Transverse thoracic muscle plane block (TTMPB) using liposomal bupivacaine and bupivacaine mixture

Liposomal bupivacaine and bupivacaine mixture were used for transverse thoracic muscle plane block (TTMPB) in experimental group.

PROCEDURE

Transverse thoracic muscle plane block (TTMPB) using bupivacaine hydrochloride

Bupivacaine hydrochloride was used for transverse thoracic muscle plane block (TTMPB) in active control group.

Sponsors & Collaborators

  • Tongji Hospital

    lead OTHER

Principal Investigators

  • Mei Wei, M.D. · Tongji Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-24
Primary Completion
2024-10-24
Completion
2026-10-12

Countries

  • China

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06646172 on ClinicalTrials.gov