Integrating Telehealth to Advance Lung Cancer Screening

Summary

The goal of this pragmatic trial is to learn if telehealth strategies can increase shared decision-making (SDM) for lung cancer screening (LCS). It will also learn about the equity of these strategies by conducting non-inferiority analysis by race and sex. The main questions it aims to answer are:

1. Does patient outreach using synchronous and asynchronous telehealth strategies increase completion of SDM visits for LCS?
2. Is the effectiveness of these telehealth strategies similar by race and sex?

The study uses a Sequential Multiple Assignment Randomized Trial (SMART) design and includes two stages of interventions. The first stage of intervention includes direct patient outreach with an invitation to schedule either a 1) telehealth SDM visit or 2) telehealth or in-person SDM visit. Participants that do not respond to the first stage interventions receive a text message reminder encouraging SDM visit completion with or without digital care coordination.

Conditions

• Early Detection of Cancer
• Telemedicine
• Decision Making

Interventions

BEHAVIORAL

Active Choice

The participant will be send a letter inviting them to complete a SDM visit either in-person or via telehealth.

BEHAVIORAL

Telehealth Only

The participant will be send a letter inviting them to complete a SDM visit via telehealth only.

BEHAVIORAL

Low Touch Strategy

Patient will be sent asynchronous text messaging reminders encouraging SDM for LCS using framed messaging.

BEHAVIORAL

High Touch Strategy

Patient will be sent asynchronous text messaging reminders encouraging SDM for LCS using framed messaging in combination with synchronous telephone-based digital care coordination.

Sponsors & Collaborators

• National Institutes of Health (NIH)

  collaborator NIH

• National Cancer Institute (NCI)

  collaborator NIH

• Abramson Cancer Center at Penn Medicine

  lead OTHER

Principal Investigators

• Katharine Rendle, PhD · Abramson Cancer Center

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE

Model

SEQUENTIAL

Eligibility

Min Age

50 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-07-09

Primary Completion

2027-01-31

Completion

2027-01-31

Countries

• United States

Study Locations