Vascular Regenerative Cell Exhaustion in Adults with Peripheral Artery Disease (PAD-VRCE)
NCT06626646 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 40
Last updated 2024-10-04
Summary
PAD-VRCE is an observational, cross-sectional, two arm study aimed at determining if the presence of peripheral artery disease (PAD) can influence the number of circulating regenerative cells in blood. From peripheral blood samples, circulating progenitor cell content will be assessed via flow cytometry and compared between individuals with PAD and individuals without PAD. Ultimately, this study plans to evaluate the relationship between PAD, vascular regenerative cell exhaustion and overall cardiovascular health.
Conditions
- Peripheral Vascular Diseases
- Cardiovascular Disease
- Type 2 Diabetes
- Peripheral Artery Disease
Sponsors & Collaborators
-
Canadian Medical and Surgical Knowledge Translation Research Group
lead OTHER
Principal Investigators
-
Subodh Verma, MD · University of Toronto
-
David A Hess, PhD · Western University, Canada
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-10-31
- Primary Completion
- 2025-07-31
- Completion
- 2025-07-31
Countries
- Canada
Study Locations
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