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Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation

NCT06619093 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2025-01-15

No results posted yet for this study

Summary

Sickle cell disease is characterized by chronic hemolytic anemia and blood rheological alterations. In addition, blood coagulation abnormalities have been reported in patients with sickle cell disease and hemolysis-derived products could be involved. The investigators hypothesized that patients with sickle cell disease and severe hemolysis (Lactate Dehydrogenase level \> 484 IU/L) could have an increased risk of hypercoagulable state and subsequent thromboembolic complications.

Conditions

  • Sickle Cell Disease (SCD)

Interventions

OTHER

blood sampling

3 additional citrate tubes (2.7mL)

Sponsors & Collaborators

  • Laboratoire Interuniversitaire de Biologie de la Motricité (UCBL1) UR7424

    collaborator UNKNOWN

  • Hospices Civils de Lyon

    lead OTHER

Eligibility

Min Age
8 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-01
Primary Completion
2028-02-01
Completion
2028-02-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06619093 on ClinicalTrials.gov