STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair

Summary

The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes. Mono-factor interventions targeting and improving these risky lifestyles have been shown to reduce the risk at surgery, but there is a lack of systematic assessment of all five lifestyles of the patient before surgery and related optimization.

This study aims to evaluate the effect of intensive combined lifestyle interventions (the STRONG programme) compared with treatment as usual in patients undergoing ventral hernia repair on postoperative complications, health, and costs on short and longer term.

The hypothesis is that the STRONG programme will halve the complication rates within 30 days.

Conditions

• Ventral Hernia
• Surgery
• Risk Reduction
• Lifestyle
• Postoperative Complications
• Prehabilitation

Interventions

BEHAVIORAL

Prehabilitation (the STRONG programme)

Participants screened positive for one or more SNAP factors and randomised to the intervention group will receive an individualised plan for prehabilitation of their specific SNAP factors.

Sponsors & Collaborators

• Copenhagen University Hospital at Herlev

  collaborator OTHER

• Zealand University Hospital

  collaborator OTHER

• Holbaek Sygehus

  collaborator OTHER

• Bispebjerg Hospital

  lead OTHER

Principal Investigators

• Hanne Tønnesen, Professor MD · WHOCC, The Parker Institute, Bispebjerg-Frederiksberg Hospital, RegH, Copenhagen

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-03-04

Primary Completion

2026-03-01

Completion

2028-03-01

Countries

• Denmark

Study Locations