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NoPro - Norwegian Hernia Prophylaxis Study

NCT06858020 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2025-03-05

No results posted yet for this study

Summary

A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh. The primary endpoint is the incidence of incisional hernias in both groups after one year.

Conditions

  • Incisional Hernia After Midline Laparotomy
  • Quality of Life (QOL)
  • Burst Abdomen
  • Surgical Site Infections

Interventions

PROCEDURE

Prophylactic polypropylene onlay mesh

The patients in the mesh group are closed with small bites technique and in addition receiving an onlay polypropylene mesh when closing the fascia in midline laparotomies.

Sponsors & Collaborators

  • Sykehuset Innlandet HF

    lead OTHER

Principal Investigators

  • Lars Martin Rekkedal, MD BBA · Chief of surgery Hamar Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-02-17
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06858020 on ClinicalTrials.gov