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Genomics and Microbiome Investigation in Cases of Recurrent Pregnancy Losses

NCT06604338 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2024-09-19

No results posted yet for this study

Summary

Recurrent pregnancy losses (RPL) are characterized by the occurrence of more than one spontaneous pregnancy loss. It is caused by different known factors, but about half of the cases remain without an explanation. Efforts are being done in the scientific community to solve this cases. In this study, the investigators aim to investigate genetic factors that might predispose to RPL, as well as the influence of the uterine microbiota (microorganisms that normally live in the uterus of women).

Conditions

  • Recurrent Pregnancy Loss(RPL)

Interventions

DIAGNOSTIC_TEST

Exome test

An exome will be performed on the participants of RPL group.

DIAGNOSTIC_TEST

Microbiota analysis

A cervical microbiota analysis will be performed in the RPL and control groups.

Sponsors & Collaborators

  • UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL (UFRGS)

    collaborator UNKNOWN

  • Hospital de Clinicas de Porto Alegre

    lead OTHER

Principal Investigators

  • Lucas Rosa Fraga, PhD, Professor · Hospital de Clínicas de Porto Alegre

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-14
Primary Completion
2024-07-05
Completion
2025-12-31

Countries

  • Brazil

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06604338 on ClinicalTrials.gov