The Role of Prothrombin Gene and Methylenetetrahydrofolate Reductase(MTHFR) Gene Polymorphisms as Risk Factors for Recurrent Miscarriage
NCT03209063 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 285
Last updated 2022-06-30
Summary
Recurrent miscarriage is a pregnancy loss before 20 weeks of gestation. The recurrent pregnancy loss(RPL) usually occurring in the first trimester of gestation and its rate is quite high (15-20% even in full reproductive period) . In 2012, the American Society for Reproductive Medicine Practice Committee issued a statement that defined recurrent pregnancy loss as a disease distinct from infertility defined by two or more failed consecutive pregnancies.approximately 40% of couples will have an etiology identified that could be associated with their loss.
Conditions
- Recurrent Miscarriage
Interventions
- DIAGNOSTIC_TEST
-
polymerase chain reaction
diagnostic test as Polymerase chain reaction for detection of Prothrombin gene and methylenetetrahydrofolate reductase gene polymorphisms
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Ghada M Mahran, MD · Assiut University, Faculty of medicine
Eligibility
- Min Age
- 17 Years
- Max Age
- 35 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-07-01
- Primary Completion
- 2022-08-01
- Completion
- 2022-09-30
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