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Improving Disease Prevention Strategies by Integrating Socio-spatial Characterization of Human Mobility

NCT06599970 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 810

Last updated 2026-04-22

No results posted yet for this study

Summary

In contrast to the trend expected based on existing prediction models, dengue incidence was historically low during the pandemic mobility restrictions of 2020-2021 in most dengue endemic countries. This highlights that current transmission models do not correctly take human mobility into account. Within a pilot-study in Cienfuegos, South-Central Cuba, we will characterise the epidemiological spread and distribution of dengue outbreaks (2012-2025) in districts repeatedly involved in previous dengue outbreaks as initiating, case-concentrating or transmission sustaining areas. This will be linked with fine-grained mobility data and socio-spatial characterizations of commuting flows and population hubs where people are concentrated during day-time (time when transmission happens). This information, together with entomological and environmental risk-data, will be used to i) improve the accuracy of mathematical dengue models, ii) better understand the transmission process and iii) inform and improve the design of disease control strategies. The project will contribute to much-needed evidence-based guidance for public health actors on improved prevention strategies of epidemics dispersion and where and when to implement control measures.

Conditions

  • Dengue
  • Arbovirus Infections
  • Epidemic Disease
  • Behavior, Health

Interventions

OTHER

No intervention

This is an observational study. No experimental interventions included. The mobility of people will be studied.

Sponsors & Collaborators

  • Cienfuegos Provincial Ministry of Health, Cuba

    collaborator UNKNOWN

  • University Ghent

    collaborator OTHER

  • Institute Pedro Kouri, Ministry of Public Health (Cuba)

    collaborator UNKNOWN

  • Institute of Tropical Medicine, Belgium

    lead OTHER

Principal Investigators

  • Veerle Vanlerberghe · Institute of Tropical Medicine

Eligibility

Min Age
19 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-06-01
Primary Completion
2026-12-31
Completion
2027-06-30

Countries

  • Cuba

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06599970 on ClinicalTrials.gov