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Innovative Drug Delivery Nanophotonic Platform for Implementation of Sarcoma Therapy

NCT06599957 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2025-09-22

No results posted yet for this study

Summary

DEEPLY aims to improve sarcoma therapy by the development of an innovative nanophotonic delivery approach to be applied in the future as an integrated local therapy for patients with inoperable tumors or with oligometastases. The major aim of the project is the development of innovative nanocarriers loaded with chemotherapeutic agents, whose delivery will be improved by the use of an optic fiber (optoporation). After the synthesis, and characterization of NPs, a prototype will be produced and preclinically validated on patient-derived biological material. This wide comprehensive methodological approach will ensure the obtainment of robust data to be faster exploited toward clinical applications.

Conditions

  • Bone and Soft Tissue Tumors

Sponsors & Collaborators

  • Università Degli Studi del Sannio Dipartimento di Ingegneria Benevento

    collaborator UNKNOWN

  • IRCCS Istituto Romagnolo per lo Studio dei Tumori Dino Amadori Meldola

    collaborator UNKNOWN

  • Istituto Ortopedico Rizzoli

    lead OTHER

Eligibility

Min Age
2 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-30
Primary Completion
2026-08-30
Completion
2026-08-30

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06599957 on ClinicalTrials.gov