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Epidemiological Studies and Risk Factor Analysis of GERD in Xiamen City

NCT06585176 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1625

Last updated 2026-03-13

No results posted yet for this study

Summary

Gastroesophageal Reflux Disease (GERD) is a condition characterized by the reflux of gastric and duodenal contents into the esophagus, primarily manifested by symptoms such as acid regurgitation and heartburn. GERD significantly affects patients' daily lives and health-related quality of life. Prolonged gastroesophageal reflux can lead to repeated irritation of the esophageal mucosa by gastric acid and acidic gastric contents, resulting in the replacement of normal squamous epithelium in the lower esophagus with metaplastic columnar epithelium. This pathological change, known as Barrett's Esophagus (BE), is considered a precancerous lesion for esophageal adenocarcinoma.

Conditions

  • Gastroesophageal Reflux Disease
  • Epidemiology
  • Risk Factors

Interventions

OTHER

No intervention

This concerns a natural history study. No interventions will be used.

Sponsors & Collaborators

  • Zhongshan Hospital (Xiamen), Fudan University

    lead OTHER

Principal Investigators

  • Wei Jiang, Doctor · Zhongshan Hospital (Xiamen), Fudan University

Eligibility

Min Age
16 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-01
Primary Completion
2025-10-31
Completion
2025-10-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06585176 on ClinicalTrials.gov